Anti-TNF therapy - A sure short way to curb RA
TNF alpha –
TNF alpha is a highly potentcytokine, and acts as a key mediator that triggers body’s natural responses to systemic inflammation. TNF alpha is mainly produced by activated macrophages. It also causes inflammation and subsequent tissue destruction in patients with rheumatic/immune diseases. It can induce fever, apoptotic cell death, cachexia, etc. Excess amounts of TNF results in several disease like Alzheimer’s disease, IBD, and cancer.
Anti-TNF and rheumatoid arthritis
While no health expert can guarantee a complete cure from RA, anti-TNF therapies that are used currently curb RA conditions from worsening. It helps patients regain their health through FDA-approved and widely recommended TNF inhibitor drugs. Development of Anti-TNF drugs and therapies are notable milestones in the development of curable treatments and medications for rheumatoid arthritis patients.
TNF inhibitor drugs are licensed biologic treatments that target the inflammatory cytokines in the body, and curb severe and unbearable inflammatory conditions caused by rheumatoid arthritis. However, these drugs are used in optimal levels, in order to avoid the possibilities of toxicity and related side effects.
Mode of action:
Anti-TNF drugs inhibit the unnatural inflammatory processes caused by TNF, an inflammatory cytokine. Excess levels of TNF results in destructive inflammatory processes that leaves serious damages on articular cartilages and bones. Anti-TNF drugs are can help inhibit the unnatural actions of TNF, thus curbing the inflammatory disease process quickly and effectively.
The U.S. Food and Drug Administration has given their nod of approval to five anti-TNF drugs that help treat moderate to severe RA. Here are three main TNF inhibitor drugs that are commonly used in rheumatoid arthritis treatments:
Although Anti-TNF drugs are tad bit pricey, these medications can help reduce the need for surgery and other complex therapies, thus promising longevity and health. However, these medicines can be used only according to the appropriate guidelines of a specialist.
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